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State of evidence · Updated Jul 23, 2026

Biohacking

Cold exposure, red light, fasting protocols, self-quantification.

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Jul 23, 2026Last update
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Latest finding · Jul 23, 2026

Are Sugar Alcohols Safe? The Erythritol Clot Question

For years, sugar alcohols — the polyols behind almost every “keto,” “zero-sugar,” and diabetic-friendly product on the shelf — were the boring, safe choice: sweet like sugar, barely any calories, and next to no effect on blood glucose.

3 Moderate1 Emerging1 Hype
2026
Jul 22, 2026

Continuous Ketone Monitors: Worth It or Hype?

For a decade the continuous glucose monitor (CGM) has been the flagship metabolic wearable, and now a sibling has arrived: the continuous ketone monitor, or CKM — a small sensor you wear on the back of the arm that tracks beta-hydroxybutyrate (BHB, the main…

1 Moderate2 Emerging1 Weak1 Hype
Jul 08, 2026

Binaural Beats: Do They Actually Work?

Here is the honest version, up front. Binaural beats are one of the strangest, most genuinely interesting audio phenomena you can experience on a pair of headphones — play one tone in your left ear and a slightly different one in your right, and your brain …

1 Emerging3 Weak1 Hype
Jul 05, 2026

Nasal Breathing: Is Nose Better Than Mouth?

Close your mouth and breathe through your nose — the books and podcasts promise it will transform your oxygenation, your endurance, and your health. Some of that is real.

1 Moderate2 Emerging1 Weak1 Hype
Jul 03, 2026

Blue-Light Glasses: Do They Actually Work?

I wanted these to work. Amber lenses are cheap, harmless, and pitched at a problem — screens wrecking our eyes and our sleep — that feels obviously true.

1 Moderate1 Emerging2 Weak1 Hype
Jun 30, 2026

Neurofeedback: Can a Headband Train Your Brain?

Slip on a slim headband, close your eyes, and an app reads your brainwaves in real time — rain falls when your mind wanders, calms when it settles. Muse and its competitors promise to turn that loop into a sharper, calmer, more optimized brain.

1 Moderate2 Emerging1 Weak1 Hype
Jun 28, 2026

Fasting-Mimicking Diet: Does ProLon Really Work?

Valter Longo’s five-day “fast with food” — sold as ProLon — is one of the rare longevity products with actual human randomized trials behind it.

3 Moderate1 Emerging1 Weak
Jun 24, 2026

Hyperbaric Oxygen: Can a Chamber Reverse Aging?

A pressurized chamber and 100% oxygen is one of the oldest pieces of established medicine on the longevity shelf — and one of the most oversold. It genuinely heals wounds that won’t close and saves divers from the bends.

1 Strong2 Emerging2 Weak
Jun 24, 2026

Epigenetic Age Tests: Do They Really Work?

Spit in a tube, mail it off, and a few weeks later a report tells you your “biological age” — sometimes younger than your birth certificate, sometimes alarmingly older — along with a number for how fast you’re aging and whether your latest protocol is “reve…

1 Moderate1 Emerging3 Weak
Jun 21, 2026

Bryan Johnson Blueprint: Does Don't Die Work?

A 48-year-old tech millionaire spends roughly two million dollars a year, swallows more than a hundred pills a day, eats his last meal before most people leave the office, and says he has reversed his aging by a couple of decades.

1 Strong2 Moderate2 Weak1 Hype
Jun 17, 2026

Exogenous Ketones: Do Keto Gummies Actually Work?

BHB salts, ketone esters, and the new wave of apple-cider-vinegar “keto gummies” are sold as a shortcut into fat-burning ketosis — weight loss in a drink, no diet required.

2 Moderate1 Emerging2 Weak1 Hype
Jun 12, 2026

Cold Showers: Do They Boost Metabolism, Mood, Immunity?

The daily cold shower is sold as a fat-loss hack, a mood cure, and an immune shield. Strip the hype and a narrower, honest picture remains: a cheap hormetic stressor with a real alertness jolt, a modest sick-day signal, and almost no case as…

2 Emerging3 Weak
Jun 09, 2026

NAD+ IV Drips: Does Infusing NAD+ Do Anything?

Walk into a wellness clinic and you can now buy an “NAD+ drip” for anywhere from $200 to $1,000 a session, sold for energy, anti-aging, brain fog, hangover recovery, even kicking addiction.

2 Moderate2 Weak1 Hype
Jun 09, 2026

Breathwork: What Wim Hof and Box Breathing Do

One of these has real trial evidence. One is plausible but barely tested. One produces genuine physiology and then gets oversold into disease cures — with a safety rule you cannot skip. Here's the calibrated read.

2 Moderate2 Emerging1 Weak
Jun 08, 2026

HRV Score: What Your Wearable Actually Tells You

Heart-rate variability is the rare wellness metric with real physiology behind it — a genuine window onto your autonomic nervous system, validated across decades of cardiology.

2 Moderate1 Emerging1 Weak1 Hype
Jun 08, 2026

Grounding (Earthing): Does Walking Barefoot Help?

Grounding — or earthing — is one of wellness culture’s most viral ideas: press your bare skin to the ground, the story goes, and a flow of electrons from the earth quiets inflammation, deepens sleep, thins your blood, and rebalances your body.

1 Moderate3 Weak1 Hype
Jun 08, 2026

Glucose Goddess Hacks: Which Anti-Spike Tricks Work

The “Glucose Goddess” phenomenon has put one idea into millions of kitchens: blunt your blood-sugar spikes and your life gets better. Walk after meals, drink vinegar before them, eat your vegetables first, swap the sweet breakfast for a savory one.

1 Moderate2 Emerging1 Weak1 Hype