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Dual GIP/GLP-1 agonist

Tirzepatide reconstitution.

Compounded tirzepatide vials are typically 10 mg, 15 mg, or 30 mg. With 2 mL of bacteriostatic water, every standard titration dose lands on a clean unit mark on a U-100 syringe.

Unit marks on a U-100 insulin syringe — 2 mL bacteriostatic water
Dose10 mg vial15 mg vial30 mg vial
2.5 mg50units33.3units16.7units
5 mg100units66.7units33.3units
7.5 mgover 100u100units50units
10 mgover 100uover 100u66.7units
12.5 mgover 100uover 100u83.3units
15 mgover 100uover 100u100units

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Tirzepatide specifics

What to know about this peptide.

Half-life

Half-life ~5 days. Once-weekly injection. Plateau in 4-5 weeks at a fixed dose.

Stability after mixing

Refrigerate at 2-8°C after reconstitution. Use within 28 days per stability data.

Typical use

Weight management, type 2 diabetes. Outperforms semaglutide head-to-head for weight loss. Titration: 2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg weekly, 4 weeks per step.

Not medical advice

The math on this page is correct for the listed vial and BAC-water volume. The decision to reconstitute and inject Tirzepatide belongs to you and a clinician who knows your full history — not to a webpage.

Frequently asked

Tirzepatide questions

What vial size is Tirzepatide usually sold in?

Tirzepatide most commonly ships as 10 mg or 15 mg or 30 mg of lyophilized powder. The standard reconstitution is 2 mL of bacteriostatic water, which yields clean unit-mark math on a U-100 insulin syringe for the doses used in most protocols.

How much bacteriostatic water do I add to a Tirzepatide vial?

The standard volume is 2 mL of bacteriostatic water. You can use more (easier to draw, lower concentration) or less (more concentrated, smaller draw volume) without changing the peptide itself — only the syringe math changes. The dose table on this page is pre-calculated for 2 mL.

What is the half-life of Tirzepatide?

Half-life ~5 days. Once-weekly injection. Plateau in 4-5 weeks at a fixed dose.

How long does reconstituted Tirzepatide last in the fridge?

Refrigerate at 2-8°C after reconstitution. Use within 28 days per stability data.

What is Tirzepatide typically used for?

Weight management, type 2 diabetes. Outperforms semaglutide head-to-head for weight loss. Titration: 2.5 → 5 → 7.5 → 10 → 12.5 → 15 mg weekly, 4 weeks per step.

What syringe should I use for Tirzepatide?

U-100 insulin syringes (29–31 gauge, 8–13 mm needle) are standard for subcutaneous peptide injection. Each unit on a U-100 syringe equals 0.01 mL. The dose table above shows how many units to draw for each common dose, given the vial size and standard bacteriostatic water volume.

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Other reconstitution guides.

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