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GLP-1 receptor agonist

Semaglutide reconstitution.

Compounded semaglutide is shipped in 2 mg, 5 mg, or 10 mg lyophilized vials. The most common reconstitution is 1 mL of bacteriostatic water, giving clean unit-mark math at every standard dose step.

Unit marks on a U-100 insulin syringe — 1 mL bacteriostatic water
Dose2 mg vial5 mg vial10 mg vial
250 mcg12.5units5units2.5units
500 mcg25units10units5units
1 mg50units20units10units
1.7 mg85units34units17units
2.4 mgover 100u48units24units

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Semaglutide specifics

What to know about this peptide.

Half-life

Long half-life (~7 days) — once-weekly dosing standard. Effects accumulate for 4-5 weeks before plateau.

Stability after mixing

After reconstitution, refrigerate at 2-8°C. Manufacturer guidance: use within 28 days. Compounded versions vary — verify with your provider.

Typical use

Weight management, type 2 diabetes. Standard titration: 0.25 mg → 0.5 mg → 1.0 mg → 1.7 mg → 2.4 mg weekly, 4 weeks at each step.

Not medical advice

The math on this page is correct for the listed vial and BAC-water volume. The decision to reconstitute and inject Semaglutide belongs to you and a clinician who knows your full history — not to a webpage.

Frequently asked

Semaglutide questions

What vial size is Semaglutide usually sold in?

Semaglutide most commonly ships as 2 mg or 5 mg or 10 mg of lyophilized powder. The standard reconstitution is 1 mL of bacteriostatic water, which yields clean unit-mark math on a U-100 insulin syringe for the doses used in most protocols.

How much bacteriostatic water do I add to a Semaglutide vial?

The standard volume is 1 mL of bacteriostatic water. You can use more (easier to draw, lower concentration) or less (more concentrated, smaller draw volume) without changing the peptide itself — only the syringe math changes. The dose table on this page is pre-calculated for 1 mL.

What is the half-life of Semaglutide?

Long half-life (~7 days) — once-weekly dosing standard. Effects accumulate for 4-5 weeks before plateau.

How long does reconstituted Semaglutide last in the fridge?

After reconstitution, refrigerate at 2-8°C. Manufacturer guidance: use within 28 days. Compounded versions vary — verify with your provider.

What is Semaglutide typically used for?

Weight management, type 2 diabetes. Standard titration: 0.25 mg → 0.5 mg → 1.0 mg → 1.7 mg → 2.4 mg weekly, 4 weeks at each step.

What syringe should I use for Semaglutide?

U-100 insulin syringes (29–31 gauge, 8–13 mm needle) are standard for subcutaneous peptide injection. Each unit on a U-100 syringe equals 0.01 mL. The dose table above shows how many units to draw for each common dose, given the vial size and standard bacteriostatic water volume.

More peptides

Other reconstitution guides.

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