Next-gen incretin
Retatrutide is currently investigational — research-purpose-only vials typically ship at 10 mg or 20 mg. Standard reconstitution mirrors tirzepatide: 2 mL bacteriostatic water for clean dosing math.
| Dose | 10 mg vial | 20 mg vial |
|---|---|---|
| 2 mg | 40units | 20units |
| 4 mg | 80units | 40units |
| 8 mg | over 100u | 80units |
| 12 mg | over 100u | over 100u |
Open the live calculator — change any value and the unit-mark math updates instantly.
Half-life ~6 days. Once-weekly. Steady-state takes 4-5 weeks per dose step.
Refrigerate after reconstitution. Treat as 28-day stability unless manufacturer guidance differs.
Investigational (Phase 3). Most aggressive weight loss in trial data to date. Off-label/research use only currently.
The math on this page is correct for the listed vial and BAC-water volume. The decision to reconstitute and inject Retatrutide belongs to you and a clinician who knows your full history — not to a webpage.
Retatrutide most commonly ships as 10 mg or 20 mg of lyophilized powder. The standard reconstitution is 2 mL of bacteriostatic water, which yields clean unit-mark math on a U-100 insulin syringe for the doses used in most protocols.
The standard volume is 2 mL of bacteriostatic water. You can use more (easier to draw, lower concentration) or less (more concentrated, smaller draw volume) without changing the peptide itself — only the syringe math changes. The dose table on this page is pre-calculated for 2 mL.
Half-life ~6 days. Once-weekly. Steady-state takes 4-5 weeks per dose step.
Refrigerate after reconstitution. Treat as 28-day stability unless manufacturer guidance differs.
Investigational (Phase 3). Most aggressive weight loss in trial data to date. Off-label/research use only currently.
U-100 insulin syringes (29–31 gauge, 8–13 mm needle) are standard for subcutaneous peptide injection. Each unit on a U-100 syringe equals 0.01 mL. The dose table above shows how many units to draw for each common dose, given the vial size and standard bacteriostatic water volume.